Corona Virus

posted Apr 27, 2014, 1:01 PM by Internal Medicine Department Kasr Alainy   [ updated Apr 27, 2014, 1:25 PM ]

Unraveling the Mysteries of Middle East Respiratory Syndrome Coronavirus

Also Get this resume of what was presented in the Coated from the article presented in the 24 th  conference of Egyptian society of internal Medicine , Date 27.2.2014

Adrenaline for out-of-hospital cardiac arrest resuscitation

posted Apr 21, 2014, 12:38 PM by Yasser Mohamed Abdelhamid

ACLS (CPR) guidelines are published every 4-5 years , the previous guidelines published in NOV 2010 removed Atropine from the armamentarium used for treating cardiac arrest patients. These changes lead to leaving Adrenaline as the main medication used in cardiac arrest patients but a recent meta- analysis that involved more than 12000 outside hospital cardiac arrest victims found that Adrenaline iv injections doesn’t improve neurologic outcome or survival till hospital admission . Till now we continue to use iv adrenaline in CPR but will that change in the future? Time will tell………

A book is closed and another one is opened in the field of oncology

posted Mar 18, 2014, 12:13 PM by Yasser Mohamed Abdelhamid   [ updated Mar 18, 2014, 12:19 PM ]

This year the Science magazine hailed a major break through in the field of oncology that appeared  to the surface this year.

Cancer immunotherapy aiming to initiate a fierce immune attack on cancer cells instead of  the traditional immunosuppressive anticancer therapy.

Novel Anticoagulants

posted Mar 13, 2014, 12:39 PM by Yasser Mohamed Abdelhamid   [ updated Mar 18, 2014, 12:14 PM ]

Four 'New' Oral Anticoagulant Stroke-Protection Benefits in AF Cut Across Subgroups in Meta-Analysis.

dabigatran (Pradaxa),  rivaroxaban (Xarelto), apixaban (Eliquis), and edoxaban (Lixana).More effective and more safe than warfarin

Role of Short Term Corticosteroids on Acute COPD Exacerbations

posted Mar 9, 2014, 1:27 PM by Yasser Mohamed Abdelhamid   [ updated Mar 18, 2014, 12:18 PM ]

Expert guidelines recommend 10-14 days systemic corticosteroids for treatment of COPD exacerbations. But this is based largely on one clinical trial more than a decade ago, which did not examine shorter treatment courses. 

Steroids help resolve COPD exacerbations, and probably save lives. But steroids cause hyperglycemia, which can be harmful, and regular (long-term) use of corticosteroids is linked to higher mortality in people with COPD

Swiss researchers Jörg D. Leuppi et al add their piece to the puzzle in the May 2013 JAMA .They randomized 314 people mostly with severe COPD (mean FEV1 31%) having severe COPD exacerbations to receive either 5 days of 40 mg prednisone followed by 9 days of placebo, or 14 days of 40 mg prednisone.

They found no statistically significant difference between the short and the long treatment courses regarding frequency of exacerbations , time till next exacerbation, need for mechanical ventilation, hyperglycaemia or mortality

Will that study change the way you treat COPD exacerbations?

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